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    • Highlights

    (Courtesy of J. Chen et al., Nat. Methods; doi:10.1038/s41592-023-01820-3)
    FIGURE 1. An optomechanical design of the SMURF two-photon microscope.
    Bio&Life Sciences

    A brain imaging trifecta

    Justine Murphy
    July 13, 2023
    An approach to imaging electrical activity deep in the brain makes neurological studies more effective and less invasive.
    Hubner Photonics
    Lasers & Sources

    Single-frequency laser offers up to 1 W output power

    LFW Staff
    July 5, 2023
    The Cobolt Jive 561 nm continuous-wave (CW) single-frequency diode-pumped laser operates at 561.2 nm.
    (Courtesy of Lumicell)
    FIGURE 1. Lumicell’s LUMISIGHT optical imaging agent and direct visualization system assists surgeons in detecting residual cancer after surgery.
    Bio&Life Sciences

    Fluorescence imaging system may improve cancer care

    Justine Murphy
    June 12, 2023
    Currently under review by the U.S. FDA, a handheld imaging probe may help surgeons detect residual cancer after surgery via a contrast agent.
    E Con Systems
    Detectors & Imaging

    Monochrome camera provides IR and near-IR sensitivity

    LFW Staff
    May 30, 2023
    The See3CAM_50CUGM Sony Pregius IMX264 global-shutter monochrome camera includes back-illuminated technology and a 3.45 µm pixel size.
    Horiba Scientific
    Test & Measurement

    Fluorescence analyzers add pulse processing algorithm feature

    LFW Staff
    April 8, 2023
    The XGT-9000 Pro and XGT-9000 Expert fluorescence analyzers have improved detection systems and a patented pulse processing algorithm.
    (Courtesy of Artem Lomakin)
    FIGURE 1. BaSISS clonal maps trace cancer evolutionary lineages in space.
    Bio&Life Sciences

    Understanding cancer’s genetic makeup could halt its spread

    Justine Murphy
    Dec. 2, 2022
    A molecular microscopy technique is helping researchers more effectively identify cellular DNA and RNA in breast cancer cells. This could lead to development of new treatments...
    (Courtesy of Abraham Beyene, Howard Hughes Medical Institute Janelia Research Campus)
    A schematic of DopaFilm shows spatially resolved hotspots of activity (top) and DopaFilm’s fluorescent nanosensors glow brighter when exposed to dopamine (bottom).
    Bio&Life Sciences

    Material made of fluorescent nanosensors may boost neural discoveries

    Justine Murphy
    Oct. 26, 2022
    By measuring the release of dopamine and other neurotransmitters, a composite material can help provide a better understanding of chemical neurotransmission.
    Teledyne Princeton Instruments
    Detectors & Imaging

    CCD cameras feature deep-depletion design

    LFW Staff
    April 24, 2022
    The LANSIS 261 CCD cameras also feature a 30.72 × 3.96 mm sensor.
    Tomocube Squid Reflectins
    Fluorescence

    Optical refractive index of live cells could have use as molecular probes

    BioOptics World Editors
    Oct. 7, 2020
    By changing this intrinsic physical property of the cell, microscopists could soon be using the refractive indices of live cells as molecular probes.